How dietary flavonoids can prevent neurodegenerative disease

Flavonoids are plant-derived compounds that have been indicated by recent studies to protect against age-related cognitive decline and neurodegeneration. Here, I discuss the cellular and molecular mechanisms suggested to underpin the positive effects of flavonoids on the brain. The burden of neurodegenerative disease has evidently increased in our ageing population – Alzheimer’s disease is set … Read more

Immunotherapy for allergy: novel strategies

In my previous article I summarised the latest ideas for preventing food allergy in early human life, and I gave an honourable mention for treating established food allergies too. Here, I further discuss immunotherapy as an allergy treatment method, focusing on alternative routes of immunotherapy that could minimise evident safety concerns whilst improving treatment effectiveness. … Read more

Dementia may be predicted via gut bacteria ‘signature’ and high-fat diet

Mice genetically prone to developing dementia demonstrate a distinct gut bacteria profile that is enhanced by a coincident high-fat diet, a new study finds. Background to the gut-brain barrier There is growing evidence for gut bacteria contributing to the onset of neurological disorders, through what has been termed the ‘gut-brain axis’. The gut microbiota produce … Read more

The Gut Bacteria of Cockroaches Provide a Potential Solution to Antibiotic Resistance

A new study suggests that the gut bacteria from cockroaches produce potent antibacterial compounds that could be utilised against multidrug-resistant pathogens. The Facts Antibiotic resistance has become a prominent issue in the treatment of bacterial infections, and has therefore emerged as a significant global threat to human health. An estimated 25,000 people die each year … Read more

Probiotics and Colorectal Cancer – Potential Chemoprotective Mechanisms

Utilising an experimental model in rats, a recent study has identified how probiotic intake may help prevent colorectal cancer initiation. Colorectal cancer (CRC) is the third most common cancer worldwide, so although incidence has remained stable in the UK and US since the mid-1990s, CRC remains an incredibly common cancer. Moreover, CRC incidence and mortality … Read more